Health Condition 1: B529- Plasmodium malariae malaria without complication
Conditions
Interventions
Intervention1: Malerian: 6ml orally twice daily with water for 2 weeks
Control Intervention1: Nil: Nil
Sponsors
Central Council for Research in Unani Medicine CCRUM New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of either sex of age 18-65 years. 2. Presence of axillary temperature >= 37.5°C (99.5 o F) or oral temperature of > 38 o C (100.4 o F) or history of fever during the past 24 hours. 3. Mono-infection with P. vivax confirmed by either positive blood smear (i.e. no mixed infection) or RDT (Rapid Diagnostic Test).
Exclusion criteria
Exclusion criteria: 1. Any evidence of severe malaria that would require hospitalization for treatment i.e. including: impaired consciousness, respiratory distress, severe anaemia (Hb hypotension abnormal bleeding or hypoglycaemia. (acc. to WHO definition) 2. Mixed or mono-infection with Plasmodium species other than P. vivax detected by microscopy. 3. Patients associated with other known conditions requiring long term treatment like TB, AIDS, diabetes, hypertension etc. 4. Reported allergy to any antimalarial drugs, including sulfa and artemisinin drugs. 5. Patients with Glucose-6-phosphate dehydrogenase deficiency 6. Pregnant and lactating females.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in signs and symptoms of ḤummÄ? AjÄ?miyya (Malarial Fever)Timepoint: 2 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Haematological and biochemical assessment for safety assessmentTimepoint: Investigations will be done at baseline and end of treatment | — |
Countries
India
Contacts
Public ContactDr Pradeep Kumar
Central Council for Research in Unani Medicine (CCRUM)
Outcome results
None listed