Health Condition 1: N879- Dysplasia of cervix uteri, unspecified
Conditions
Interventions
Intervention1: colposcopy followed by treatment of the abnormal suspected lesion: treatment using
a) LEEP
B) cold knife conisation
C) thermal ablation
LEEP and Thermal ablation are day care procedures
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Women aged 25-60 years suspected to have Cervical intraepithelial neoplasia on PAP Smear/Colposcopy/Clinical examination will be included in the study. Women with abnormal screening results (PAP smear with Atypical squamous cells of undetermined significance (ASCUS) or worse , positive HPV DNA, positive VIA or visual inspection with Lugolâ??s iodine) Women with clinically abnormal cervix with normal PAP smear Women with persistent inflammatory PAP smears, post coital bleeding or persistent discharge P/V
Exclusion criteria
Exclusion criteria: Inability to give informed consent Women with obvious growth on cervix. Pregnant women Women with severe debilitating disease Women with history of pelvic irradiation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the results in the two treated groups , one by â??See and Treatâ?? approach and one by conventional three step approach, in terms of initial cytology, final Histopathological diagnosis, LEEP resultsTimepoint: initially, 10 days , 6 months, 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the two colposcopy scoring systems, the Reid Colposcopy Index(RCI) and the Swede Score in terms of their specificity, sensitivity, negative predictive value and positive predictive values.Timepoint: AT baseline | — |
Countries
India
Contacts
Public ContactDr Jaya Chaturvedi
AIIMS Rishikesh
Outcome results
None listed