A study to see the additive epidural analgesic effect of two drugs dexmedetomidine & fentanyl

An observational study between Fentanyl v/s Dexmedetomidine as adjuvant to epidural ropivacaine for postoperative analgesia in spine surgery

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/05/025233

Enrollment

Registered

2020-05-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G890- Central pain syndrome

Interventions

Intervention1: Fentanyl v/s Dexmedetomidine: Fentanyl1mcg/ml with Ropivacaine 0.125%@ v/s dexmedetomidine 1mcg/ml with Ropivacaine 0.125%@ in epidural space as continuous infusion to be titrated.

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing lower thoracic (below T8)& lumbosacral spine fixation

Exclusion criteria

Exclusion criteria: 1.Refuse to participate, 2.chronic pain syndrome, 3. cardiac diseases,4.hematological disease, 5.psychiatric disease,6.allergy to local anaesthetic, 7.upper thoracic & 8.cervical spine surgery,9.tubercular spine

Design outcomes

Primary

Measure	Time frame
Analgesia using VISUAL ANALOG SCORE.Timepoint: 1year	—

Secondary

Measure	Time frame
Patients satisfaction Ramsay sedation score Heart rate Blood pressure Side effectsTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactRupak Kumar

Ptjnm medical college raipur

Drdeepakaims@gmail.com9684666444

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026