None listed
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
Rohit Walia
MEDICALgorithmics
Eligibility
Inclusion criteria
Inclusion criteria: people taking pre exposure COVID 19 hydroxychloroquin prophylaxis Written informed consent
Exclusion criteria
Exclusion criteria: Corrected QT greater than 480 ms Known congenital Long QT Co moralities and contraindications to hydroxychloroquin Retinopathy Known hypersensitivity to chloroquine Cardiomyopathy, prolonged QTc, cardiac arrhythmias • History of psoriasis, porphyria cutanea tarda Epilepsy Myasthenia gravis, myopathy of any cause Serious hepatic or renal disease Known glucose-6-phosphate dehydrogenase deficiency Current use of medication with known serious hepatotoxic effects or known interaction with chloroquine Severe depression Electrolyte imbalance Anti arrhythmic drugs Cardiac devices like pacemaker , defibrillators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| No of patients with QT prolongation by 25 percentage of baseline No of patients with QT prolongation greater than 500 ms No of patients with ventricular arrhythmias Syncope Sudden cardiac DeathTimepoint: 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Any drug related adverse events Any Syncope , all cause mortalityTimepoint: seven days | — |
Countries
India
Contacts
Public ContactRohit Walia
All India Institute of Medical Science Rishikesh
Outcome results
None listed