Comparison of effect of levonorgestrel intrauterine system vs tablet dienogest in adenomyosis

Comparison of efficacy between levonorgestrel intrauterine system and dienogest in adenomyosis - a randomised clinical trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/05/025186

Enrollment

120

Registered

2020-05-15

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N858- Other specified noninflammatory disorders of uterus

Interventions

Intervention1: Tablet Dienogest: Participants will be prescribed tab Dienogest 2 mg once daily for 3 months Control Intervention1: Levonogeatrel intrauterine system insertion (LNG - IUS): LNG - IUS wi

Eligibility

Inclusion criteria

Inclusion criteria: Age 20 years or more, Adenomyosis diagnosed by imaging

Exclusion criteria

Exclusion criteria: Ovarian endometriosis, or uterine leiomyoma diagnosed by imaging, severe anemia, Patients who are planned for hysterectomy or any other modality of treantment, Patients who want pregnancy in future, Patients with contraindication(s) to use LNG IUS or dienogest, PAtients not giviong conscent for the study

Design outcomes

Primary

Measure	Time frame
Reduction in visual analogue scale score for painTimepoint: 3 months	—

Secondary

Measure	Time frame
Change in menstrual blood loss by subjective assessment, change in quality of life by WHO BREF questionnaire, to record adverse eventsTimepoint: 3 months	—

Countries

India

Contacts

Public ContactDr Saubhagya kumar Jena

All India Institute Of Medical Sciences Bhubaneswar

obgyn_saubhagya@aiimsbhubaneswar.edu.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026