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A study on global gene expression and circulating mRNA profiling in Esophageal cancer patients

Association of global gene expression and circulating mRNA profiling with pathologic response to neoadjuvant chemoradiation in locally advanced Esophageal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/05/025172
Enrollment
50
Registered
2020-05-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: C159- Malignant neoplasm of esophagus, unspecified

Interventions

None listed

Sponsors

Dr Naveena Kumar AN
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with locally advanced esophageal cancer. Age less than 75 years and more than 18 years. Patients who are willing to give informed consent.

Exclusion criteria

Exclusion criteria: Metastatic esophageal cancer. Patient not fit for neo-adjuvant chemo-radiation and surgery. Patients with seriously ill conditions and major co-morbidities.

Design outcomes

Primary

MeasureTime frame
Gene expression and mRNA profiling in Indian Esophageal Cancer PatientsTimepoint: 3 years—

Secondary

MeasureTime frame
To assess the survival outcomes in different molecular signatures.Timepoint: 3 years—

Countries

India

Contacts

Public ContactDr Mahadev Rao

Manipal College of Pharmaceutical Sciences MAHE Manipal

mahadev.rao@manipal.edu8105706060

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026