Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention1: Homoeopathic individualized medicine in centesimal Potency.: -Experimental arm:Intervention is planned as administering indicated homoeopathic medicines centesimal potencies ,as decided
dosage and repetition depending upon the individual requirement of the cases.All medicines will be procured from a Good Manufacturing Practice(GMP)-certified firm.General management will include ice c
dosage and repetition depending upon the individual requirement of the cases .Management guidelines will be given as in the experimental arm.Duration of therapy:3 months.
Control Intervention2: Placeb
dosage and repetition depending upon the individual requirement of the cases .Management guidelines will be given as in the experimental arm.Duration of therapy:3 months.
Sponsors
State National homoeopathic Medical College and Hoapital
Eligibility
Inclusion criteria
Inclusion criteria: 1)Diagnosed knee osteoarthritis as per American College of Rheumatology (ACR)clinical/radiographic classification criteria,(sensitivity91%,specificity86%): -knee pain -At least 1 of 3:age more than 50yrs,stiffness less than 30min,and crepitus on knee motion -Osteophytes on knee x-ray 2)Patients already undergoing regular oral or topical analgesics or NSAID therapy for painful episodes of osteoarthritis ,provided the medications are stopped completely at least 2 weeks prior study entry 3)Literate patients;can read Hindi or English 4)Providing written informed consent
Exclusion criteria
Exclusion criteria: 1)Severe degeneration of knee joint with marked joint narrowing ,varus,or valgus deformity of knee ( >12degree),evedenced by imaging or otherevidences and requiring surgical intervention 2)Non-ambulant patients 3)Self -reported joint disorders other than osteoarthritis 4)Intra-articular injections within 2weeks before study entry 5)Transplanted kness 6)Recent significant knee surgeory within last 6 months 7)Patients who are too sick for consultation 8)Unwilling to take part and not giving consent to join the study 9)Unable to read patient information sheet 10)Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life 11)Pregnancy and lactation 12)Substance abuse and/or dependence 13)Self-reported immune-compromised state 14)Undergoing homoeopathic treatment for any chronic disease within last 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee injury and osteoarthritis outcome score(KOOS)Timepoint: Baseline ,every month upto 3rd month | — |
Secondary
| Measure | Time frame |
|---|---|
| European quality of life -five dimension -five level scoring(EQ-5D-5L)Timepoint: Baseline,every month upto 3rd month;Frequency of add-on Paracetamol or NSAIDsTimepoint: Baseline,every month upto 3rd month | — |
Countries
India
Contacts
Public ContactDr arvind kumar verma
State national medical college and hospital
Outcome results
None listed