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Comparision of three doses of oral gabapentin in reducing pain in patients undergoing gynecologic cancer surgeries

A Comparative study of three different doses of oral Gabapentin as â??preemptive analgesicâ?? in patients undergoing elective Gynecologic oncological surgeries under general anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/05/025131
Enrollment
75
Registered
2020-05-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C53- Malignant neoplasm of cervix uteri Health Condition 2: C54- Malignant neoplasm of corpus uteri Health Condition 3: C562- Malignant neoplasm of left ovary Health Condition 4: C56- Malignant neoplasm of ovary Health Condition 5: C561- Malignant neoplasm of right ovary Health Condition 6: C569- Malignant neoplasm of unspecifiedovary Health Condition 7: C55- Malignant neoplasm of uterus, partunspecified

Interventions

Intervention1: Gabapentin 900 mg: Dose : 900 mg, Time: 1 hour prior to surgery, Route of adminstration: Oral Intervention2: Gabapentin 1200 mg: Dose: 1200 mg Time: 1 hour prior to surgery Route of adm

Sponsors

R KAVYA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients giving valid informed consent. Patients aged between 18 â?? 65 years. Patients belonging to ASA Grade l and ll.

Exclusion criteria

Exclusion criteria: 1.Patients belonging to ASA Grade III and IV. 2.Pregnant patients. 3.Patients with known psychiatric disorders. 4.Patients on sedatives, hypnotics, antidepressant drugs. 5.Patients already taking oral Gabapentin. 6.Patients allergic to opioids and tramadol.

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of three different doses of oral Gabapentin given one hour prior to surgery as preemptive analgesic to attenuate postoperative pain in patients undergoing elective gynecologic oncological surgeries under General anaesthesia by measuring following parameters: heart rate(HR), systolic blood pressure(SBP), diastolic blood pressure(DBP), mean arterial blood pressure(MAP) , sedation score, VAS scoreTimepoint: VAS(Visual Analogue Score) score for postoperative pain will be noted at 0, 2, 4, 6, 8, 12, 16, 20, 24 hours postoperatively.—

Secondary

MeasureTime frame
To study and assess the degree of sedation with three different doses of Gabapentin using Ramsay sedation score. To study and assess the incidence of side effects like dizziness, nausea and vomiting with three different doses.Timepoint: 24 hours postoperatively—

Countries

India

Contacts

Public ContactR KAVYA

Kidwai Memorial Institute of Oncology

drrashmisatheesh@gmail.com8792406774

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026