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Study to compare different drugs with different routes in nasal surgery to compare blood loss, visiblity and better outcome.

A Placebo Controlled Study To Compare The Hypotensive Effect Of Intravenous Dexmedetomidine Infusion Versus Premedication With Oral Metoprolol Under Sevoflurane Anaesthesia For Functional Endoscopic Sinus Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/05/025037
Enrollment
90
Registered
2020-05-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J019- Acute sinusitis, unspecified

Interventions

Intervention1: intravenous dexmedetomidine infusion versus premedication with oral metoprolol for hypotensive anaesthesia in patients undergoing FESS with sevoflurane anaesthesia: to evaluate the effi

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status grade I and II

Exclusion criteria

Exclusion criteria: 1. patients on any of the study drugs prior to surgery 2. patients with known hypersensitivity to study drugs 3. patients having history of drug abuse 4. patients who are mentally retarded 5. coagulation defects 6. conditions contraindicated for induced hypotension

Design outcomes

Primary

MeasureTime frame
to evaluate the efficacy of intravenous dexmedetomidine, oral metoprolol as a premedicant with inhalational sevoflurane for inducing hypotension in terms of mean arterial blood pressure and surgical field visibilityTimepoint: baseline, every minute for first 5 minutes, every 5 minutes for next 15 minutes and then every 15 minutes till the end of surgery

Secondary

MeasureTime frame
to study the incidence of intra-operative and post-operative complications associated with study drugs or technique of induced hypotensionTimepoint: intraoperatively and upto 24 hours after surgery

Countries

India

Contacts

Public ContactDr Sukhman Kaur Gill

Sri Guru Ram Das Institute Of Medical Sciences And Research

drchawla30@yahoo.co.in9915530033

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026