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Relationship between the cell free DNA load and response to neoadjuvant chemotherapy in locally advanced breast cancer

Correlation between cell free DNA load and response to neoadjuvant chemotherapy, pathologically and radiologically in locally advanced breast cancer prospective study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/05/025015
Enrollment
75
Registered
2020-05-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

HCG Hopsital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient betwee with Locally advanced breast cancer those who are planned NACT followed by surgery [TNM III A&B,C] Histologically confirmed ca breast and studied for ER/PR/HER2/Ki67 EF >/ 50 those who are receiving anthracycline based chemotherapy

Exclusion criteria

Exclusion criteria: Metastatic breast cancer , Neoadjuvant hormal therapy, Male breast cancer

Design outcomes

Primary

MeasureTime frame
Cell free DNA LoadTimepoint: before and after the neo adjuvant chemotherapy—

Secondary

MeasureTime frame
Radiological and pathological responseTimepoint: during and after the chemotherapy—

Countries

India

Contacts

Public ContactDr Thianeshwaran S

HCG Hospital

drthianesh420@gmail.com9789740201

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026