FindTrial
Sign In

A study aimed to evaluate and compare the effect of nebulisation with two different doses of fluticasone drug before starting anaesthesia, on the occurrence and severity of sore throat (throat pain) in patients undergoing general anaesthesia with endotracheal tube.

Comparative evaluation of preoperative nebulisation with two doses of fluticasone for postoperative sore throat in patients undergoing general anaesthesia with endotracheal intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/05/024987
Enrollment
120
Registered
2020-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis Health Condition 2: N200- Calculus of kidney Health Condition 3: N731- Chronic parametritis and pelvic cellulitis Health Condition 4: N800- Endometriosis of uterus Health Condition 5: N972- Female infertility of uterine origin Health Condition 6: N132- Hydronephrosis with renal and ureteral calculous obstruction Health Condition 7: N839- Noninflammatory disorder of ovary,fallopian tube and broad ligament, unspecified Healt

Interventions

Intervention1: Nebulisation with Fluticasone drug in two different doses.: Preoperative nebulisation with Fluticasone drug solution in three groups. One group will be nebulised with 250mcg diluted to

Sponsors

Naresh Kumar Gautam
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: AMERICAN SOCIETY OF ANESTHESIOLOGISTS (ASA) PHYSICAL STATUS 1 AND 2 UNDERGOING LAPAROSCOPIC SURGERIES

Exclusion criteria

Exclusion criteria: 1. Patient with anticipated difficult airway. 2. Patients with history of preoperative sore throat, oral surgeries, asthma, COPD, diabetes, head and neck surgeries. 3.Patients with known allergies to study drugs and rescue drugs. 4. Patients consuming NSAIDS and steroidal drugs. 5. Duration of surgery less than 1 or more than 4 hours.

Design outcomes

Primary

MeasureTime frame
1. Incidence and Severity of Post Operative Sore Throat. Timepoint: 0,2,6,12,24 hours after Extubation.—

Secondary

MeasureTime frame
1. Incidence and severity of cough. 2. Incidence and severity of hoarseness of voice.Timepoint: 0,2,6,12,24 Hours after extubation—

Countries

India

Contacts

Public ContactNaresh Kumar Gautam

Vardhman Mahavir Medical College and Safdarjung Hospital

shruti.anaesth@gmail.com9212308441

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026