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The use of topical Povidone Iodine (PVP-I) oropharyngeal and intranasal application during the current coronavirus pandemic as a potential measure to reduce viral transmission

Effectiveness of topical povidone iodine (PVP-I) oropharyngeal and intranasal application during the current coronavirus pandemic amongst COVID-19 positive patients in Andhra Pradesh, India

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/05/024962
Enrollment
96
Registered
2020-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

Intervention1: Povidone Iodine: 2% Povidone Iodine gargle diluted to 1% (w/v) is used as oropharyngeal gargle and intranasal application given 4 times to 48 laboratory tested COVID-19 patients and fol

Sponsors

WIN MEDICARE PVTLTD
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients laboratory tested COVID-19 positive above 18 years of age +/- two days of admission

Exclusion criteria

Exclusion criteria: Known allergy to povidone iodine or iodine thyroid disorders pregnancy patients on Lithium therapy patients on respiratory distress / unconscious / on ventilator

Design outcomes

Primary

MeasureTime frame
comparing the reduction in the progression, transmission of disease in 48 participants taking oropharyngeal gargles and intranasal application of PVP-I in comparison to the control group not doing the same for which patients in both the group will be tested for viral load on 7 th and 21 st day. Spread of the disease can be checked by confirming if the nasal / oropharyngeryngel swabs turn negative and no contacts turn covid-19 positiveTimepoint: The study group will be tested for covid-19 to check for negativity on & 7th and 21st day following intervention

Secondary

MeasureTime frame
Early recovery from infection and no relapse of infection. patients will be tested on 7th day and 21st day to confirm if they have turned negative . early negative will be an indicative of early recovery. Also even if any of the patients have co morbid factors and they do not turn serious that will suggest that disease progression is controlledTimepoint: 12 to 14 weeks

Countries

India

Contacts

Public ContactDr Sumita Shankar

Rangaraya Medical College

sum713@yahoo.com9848184495

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 13, 2026