Health Condition 1: K801- Calculus of gallbladder with othercholecystitis Health Condition 2: K811- Chronic cholecystitis Health Condition 3: N979- Female infertility, unspecified Health Condition 4: C569- Malignant neoplasm of unspecifiedovary Health Condition 5: O- Medical and Surgical Health Condition 6: N139- Obstructive and reflux uropathy, unspecified Health Condition 7: K36- Other appendicitis Health Condition 8: N950- Postmenopausal bleeding
Conditions
Interventions
Intervention1: Dexmedetomidine: 1mcg/kg diluted in 100 ml Normal saline as slow IV 15 minutes prior to induction of anaesthesia
Control Intervention1: Placebo: 100 ml of normal saline 15 minutes pri
Sponsors
StJohns Medical college
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex undergoing elective laparoscopic surgeries,ASA I and II, Age between 20 -59 years and Patients with Mallampatti grade I or II
Exclusion criteria
Exclusion criteria: • Any known allergy to the study drug • Pregnant women • BMI >35 kg/cm2 • Patients with pre-existing neuromuscular disease. • Patients with anticipated difficult airway. • More than one intubation attempt • Baseline heart rate • Patients on beta- blockers and calcium channel blockers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effects of intravenous Dexmedetomidine and Magnesium sulphate on hemodynamic changes occurring during laryngoscopy, intubation and during pneumoperitoneum in laparoscopic surgeries.Timepoint: 15 minutes prior to induction, at the time of induction, laryngoscopy ,1,3,5,10 minutes after intubation, at the time of pneumoperitoneum , 1,5,10, 30 minutes after pneumoperitoneum | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess any associated side effects like hypotension, bradycardia, dry mouth, nausea vomiting and allergic reactions.Timepoint: 30 minutes | — |
Countries
India
Contacts
Public ContactSurbhi Gupta
St.Johns medical college
Outcome results
None listed