Herbal mouth wash to minimise radiation induced mucositis in head and neck cancer patients

Randomised controlled trial to test the efficacy of herbal mouth wash in managing acute toxicity of radiation in Head & Neck cancer patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/04/024851

Enrollment

129

Registered

2020-04-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Intervention1: Two formulations of herbal mouth wash: 3 Arm trial using 2 formulations of herbal mouthwash containing 5 plant ingredients-Emblica officinalis (dried fruit), Terminalia chebula (dried f

Eligibility

Inclusion criteria

Inclusion criteria: Patients with oral cancer undergoing radical / adjuvant radiotherapy with or without surgery will be included.

Exclusion criteria

Exclusion criteria: Patients who require adjuvant chemoradiation will not be included.

Design outcomes

Primary

Measure	Time frame
To find out whether the two forms of mouth wash is useful in minimizing side effects of radiation in patients undergoing radiotherapy for oral cancers in terms of oral hygiene, in minimising oral mucositis and in decreasing the severity of analgesic and antibiotic usage. Timepoint: At baseline, Weekly, at the end of radiotherapy treatment and 6 weeks after the treatment	—

Secondary

Measure	Time frame
degree of xerostomia, intolerance to spicy food and the tumour response.Timepoint: 6 weeks after the completion of treatment	—

Countries

India

Contacts

Public ContactDrK Ramadas

Regional Cancer Centre, Thiruvananthapuram

ramdasrcc@gmail.com9447042309

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 8, 2026