A clinical study to compare and evaluate the anti bacterial effect of 5% herbal mouthwash and 0.2% chlorhexidine mouthwash in high decay prone individuals.

A comparative evaluation of antimicrobial efficacy of 5% Echinacea angustifolia aqueous root extract and 0.2% chlorhexidine against Streptococcus mutans, Lactobacillus acidophilus and Scardovia wiggsiae as a mouth rinse on pH and buffering capacity of saliva, pH of plaque and quantification of bacteria in plaque and dentinal caries samples by real time PCR in high caries risk patients. â?? An invivo study.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/04/024840

Enrollment

314

Registered

2020-04-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 5% Echinacea angustifolia aqueous root extract: Comparing 5% Echinacea angustifolia and 0.2% chlorhexidine as a mouthrinse for assessing the pH and buffering capacity of saliva, pH of p

Eligibility

Inclusion criteria

Inclusion criteria: Age group between 13-21 yrs . 2) ASA I &II patients. 3) Patients having DMFT >5 and with at least one active carious lesion.

Exclusion criteria

Exclusion criteria: Patients who used chemical anti-plaque agents and mechanical debridement procedures or were under antibiotics therapies. 2) Patients with developmental anomalies. 3) Mentally challenged patients. 4) Patients with Xerostomia. 5) Patients undergoing fixed orthodontic appliance therapy.

Design outcomes

Primary

Measure	Time frame
Reduction in antibacterial count in plaque and dentinal caries sample -Increase in pH of saliva -Increase in buffering capacity of saliva and plaque. Timepoint: 60 mins and after 24 hr.	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr L Vijay Amirtharaj

SRM Institute of Science and Technology

reasearchmaha@gmail.com044-22490526

Outcome results