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A study to compare the effects of drugs for preventing stress response to intubation.

A comparitive study of effects of Fentanyl and Lignocaine Hydrochloride versus Paracetamol and Magnesium Sulphate in preventing stress response to intubation.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/04/024831
Enrollment
60
Registered
2020-04-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: preventing stress response to intubation: comparison of effects of IV fentanyl(2 micrograms/kg) with lignocaine hydrochloride(1.5mg/kg) and paracetamol 1 gm with magnesium sulphate 1.5m

Sponsors

DR PSIMS RF
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients belonging to ASA Grade-1&2 Patients with Mallampati Grade-1&2 Patients undergoing elective surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: ASA Grade 3&4 Mallampatti grade 3 and 4 patients with cardio-respiratory, renal, hepatic or endocrine and muscular diseases patients allergic to study drugs- Fentanyl ,Lignocaine Hydrochloride, Paracetamol and Magnesium sulphate

Design outcomes

Primary

MeasureTime frame
TO MEASURE THE HEART RATE AND BLOOD PRESSURE VARIATION WITH OPOIDS AND NON OPOIDSTimepoint: 15 MINUTES—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactDr Bhavika Borugadda

Dr Pinnamaneni Siddhartha Institute Of Medical Sciences And Research Foundation

deepthi.smily90@gmail.com9963510657

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026