Study on whether addition of heparin during cataract surgery will decrease inflammation after surgery

Effect Of Heparinised Irrigating Solution During Cataract Surgery On Postoperative Inflammation

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/04/024817

Enrollment

330

Registered

2020-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H259- Unspecified age-related cataract

Interventions

Intervention1: heparin: adding 5ml(5000IU) to 500ml of irrigating fluid during cataract surgery( intra cameral) Control Intervention1: no drug added: normal irrigating fluid used for cataract surgery

Eligibility

Inclusion criteria

Inclusion criteria: cause of vision being cataract

Exclusion criteria

Exclusion criteria: patients with uveitis & glaucoma patients with traumatic cataract, complicated cataract, congenital cataract. patients who have undergone surgeries in the past. ocular trauma pupil size less than 7mm patients on pilocarpine patients with bleeding tendencies patients on systemic anticoagulants

Design outcomes

Primary

Measure	Time frame
to document, grade and compare anterior chamber cells and flareTimepoint: to document, grade and compare anterior chamber cells and flare post day 1, 4weeks and 8 weeks postoperatively	—

Secondary

Measure	Time frame
reduction in postoperative complications like posterior synechiae and cystoid macular edema.Timepoint: 3 years	—

Countries

India

Contacts

Public ContactDR ABHISHEK GU

yes, to DMIMS university

hod.ophthalmologyjnmc@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026