Health Condition 1: M464- Discitis, unspecified
Conditions
Interventions
Intervention1: Inj Dexmedetomidine: Inj Dexmedetomidine as a continuous infusion at the rate of 0.2 mcg/kg/hr initiated at the start of surgery continued till skin closure.
Control Intervention1: Inj
Sponsors
Dr Ramyavel Thangavelu
Eligibility
Inclusion criteria
Inclusion criteria: All patients aged 18-70 years belonging to ASA 1 and 2 undergoing elective spine surgery under general anaesthesia.
Exclusion criteria
Exclusion criteria: 1) Any allergy/hypersensitivity to the study medication. 2) Patients with BMI > 30 kg/m2 3) Patients for emergency spine procedures. 4) Patients who received opioid, antiemetics or any steroid therapy 24 hrs prior to surgery. 5) Patients had episode of nausea, vomiting or retching in the 24 hrs prior to anaesthesia. 6) Patients with history of GERD
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grade of Post operative nausea vomiting (Grade 0: no nausea and no retching Grade 1: complaining of sickness or retching Grade 2: vomiting one or two times in 30 minutes Grade 3: vomiting more than two times in 30 minutes Timepoint: Grade of PONV will be recorded at 0 hrs/Baseline (immediate post surgery) 4 hrs 8 hrs 12 hrs 16 hrs 20 hrs 24 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mean arterial pressure (MAP)and Heart rate (HR). 2.Dose of additional Inj fentanyl administered 3. Concentration of inhalational agent used. 4. Grade of Sedation postoperatively. Timepoint: MAP, HR, Inj Fentanyl and Conc of Inhalational agent will be assessed at: Baseline (at start of surgery) followed by every 30 min till the end of surgery. Grade of sedation will be assessed at: At baseline (immediately post surgery) followed by every 4 hrs till 24 hrs post surgery. | — |
Countries
India
Contacts
Public ContactDr Ramyavel Thangavelu
Pondicherry Institute of Medical Sciences
Outcome results
None listed