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comparing the effectiveness of different doses of norepinephrine immediately after giving spinal anaesthesia to prevent fall in blood pressure during caesarean section.

Comparision of efficacy of two different bolus doses of norepinephrine as prophylactic to prevent postspinal hypotension during elective caesarean section.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/04/024801
Enrollment
84
Registered
2020-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O998- Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium

Interventions

Intervention1: Norepinephrine: norepinephrine 0.1 mcg/kg iv bolus Intervention2: Norepinephrine: norepinephrine 0.15 mcg/kg iv bolus

Sponsors

Kasturba medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Pregnant females undergoing elective caesarean section under spinal anaesthesia. 2.Full term pregnancy. 3.Singleton pregnancy. 4.BP range 90-140 mmHg 5.ASA physical status II 6.Age 18 years and older. 7.Weight between 50 and 100 kg. 8.Height between 150 and 170 cm.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Hypertension, cardiovascular or cerebrovascular disease. 3. Fetal abnormalities. 4. Diabetes (excluding gestational diabetes). 5. Contraindications to spinal anaesthesia

Design outcomes

Primary

MeasureTime frame
Success of prophylactic iv bolus of norepinephrine to maintain SBP at or above 80% of baselineTimepoint: from induction to delivery of foetus—

Secondary

MeasureTime frame
1.Hypertension 2.Bradycardia 3.nausea and vomiting 4. APGAR score 4.Nausea 5.Vomiting 6.Apgar score Timepoint: From induction to delivery of baby—

Countries

India

Contacts

Public ContactDr Garapati Pranathi

Kasturba Medical College, Mangaluru

madhusudan.upadya@gmail.com9845225340

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026