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Is 1% lignocaine drug similar to 2% lignocaine when used in airway anaesthesia in a routine bronchoscopy procedure?

Randomized controlled trial to study efficacy of 1% vs 2% lignocaine in topical airway anaesthesia in routine bronchoscopy procedures

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/04/024796
Enrollment
500
Registered
2020-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J00-J99- Diseases of the respiratory system

Interventions

Intervention1: 1% lignocaine used as spray as you go technique: 1% lignocaine will be used for topical airway anaesthesia as a spray as you go technique in routine bronchoscopy procedure Control Inter

Sponsors

Dr Prince James
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consecutive patients undergoing flexible bronchoscopy during study period will be considered eligible for inclusion if they are 1.Aged above 18 years 2.Hemodynamically stable(defined systolic B.P >100mmHg,

Exclusion criteria

Exclusion criteria: 1. Failure to provide informed consent 2. Documented history of lignocaine toxicity 3. Pregnancy 4. Patients undergoing TBNA and other interventions 5. Wherein bronchoscopy was performed through endotracheal or tracheostomy tube

Design outcomes

Primary

MeasureTime frame
To compare the cough scores during the procedure between two study groups that is 1% lignocaine and 2% lignocaine by using VAS score(0-100mm)Timepoint: 1.Immediately after procedure- Cough score as assessed by bronchoscopist,respiratory therapist and staff nurse assisting the procedure 2.Two hours after procedure-cough score as assessed by patient

Secondary

MeasureTime frame
To determine overall complication rate in number while undergoing bronchoscopy procedures in 1% vs 2% lignocaineTimepoint: immediately after the procedure;To determine overall feel of scopy as assessed by patient based on FACES pain scale scoreTimepoint: within 2 hours of procedure;To determine overall feel of scopy for the operator based on VAS score(0-100mm scale)Timepoint: immediately after the procedure;To determine total dose of lignocaine (in mg) used while performing procedure for 1% vs 2% concentrationsTimepoint: immediately after the procedure

Countries

India

Contacts

Public ContactDr Prince James

CMC,Vellore

drprincej@gmail.com9600771709

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026