Health Condition 1: J00-J06- Acute upper respiratory infections
Conditions
Interventions
Intervention1: Antibiotics: Throat swab will be sent on Day 1. Supportive treatment will be started on Day 1.
Tablet Levocetrizine 5 mg PO HS for 5-7 days
Tablet Levocetrizine 5mg + Montelukast 10 m
Sponsors
Department of ENT All India Institute of Medical Sciences Nagpur
Eligibility
Inclusion criteria
Inclusion criteria: 1.The patient presenting with symptoms of URTI: Runny nose Nasal congestion Headache Low-grade fever Facial pressure Sneezing The patient presenting with cough, with or without sputum, lasting for less than 2 weeks History of fever Cervical lymphadenopathy Sore throat 2.The patient whose throat swab shows positive culture for pathogenic bacteria 3.Patients willing to participate in the study and ready for follow-up. 4.Patients who are in agreement with the terms of the informed consent
Exclusion criteria
Exclusion criteria: 1)The patient who have taken antibiotic treatment for the present illness 2)Patients less than 18 years of age 3)Patients more than 60 years of age 4)The patient presenting with complication 5)The patient with other generalized illness 6) Known hypersensitivity to the contents of the drugs 7)Pregnancy or Lactation 8)Use of any antibiotic drug within the last 15 days 9)Other conditions considered by the investigator as reasonable for non-eligibility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Symptoms of URTI on day three by using Jackson symptom score . 2. Symptoms of URTI at one week (days six to eight). The illness severity during each URTI episode will be assessed daily using the Wisconsin Upper Respiratory Symptom Survey (WURSS-11 scale) Timepoint: 1. Day 3 2. Day 6-8 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Success: Cure 2. Failure: No change in, or worsening of baseline signs and symptoms requiring modification of treatment, i.e. addition of or switch to another systemic antibacterial therapy or drug. Unknown or missing values were considered as failure. 3. Time of symptom disappearance 4. Incidence of suppurative complications: i) Quinsy; ii) Acute otitis media; iii) Acute sinusitis. Timepoint: 1. Day 14 2. Day 24 3. Day 90 | — |
Countries
India
Contacts
Public ContactDr Kiran Kumar Prathipati
All India Institute of Medical Sciences, Nagpur
Outcome results
None listed