Applying marigold plant material on the open wound after removal of a small part of the gums in the mouth and comparing its healing with that of patients own blood material. -As a medical trial.

Comparative evaluation of wound healing capacity of Calendula Officinalis with that of platelet rich fibrin (PRF) at the palatal donor site after obtaining free gingival graft. -A Randomized clinical trial. - CPRF

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/04/024717

Enrollment

Registered

2020-04-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A488- Other specified bacterial diseases

Interventions

Intervention1: Use of Calendula Officinalis in wound healing after obtaining free gingival graft from the palate.: application of calendula officinalis gel at the palatal donor site after obtaining f

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to participate in the study Patients undergoing plastic surgery and requiring soft tissue graft. Good oral hygiene No history of periodontal surgery at the operation site

Exclusion criteria

Exclusion criteria: History of known systemic diseases like hypertension, diabetes, HIV, radiation therapy, immunosuppressive therapy, cancer. Pregnancy/lactation Patients with the habit of smoking and tobacco chewing Medications known to affect the outcomes of the treatment

Design outcomes

Primary

Measure	Time frame
Primary outcome:To observe wound closure according to the Healing Index and haemostasis. Secondary outcome:To record Pain perception using verbal rating scale (VRS)Timepoint: 7th day, 15th day and 2 months	—

Secondary

Measure	Time frame
Secondary outcome:To record Pain perception using verbal rating scale (VRS)Timepoint: 7th day, 15th day and 2 months	—

Countries

India

Contacts

Public ContactDR MADHURYA N KEDLAYA

Manipal College of Dental Sciences, Manipal

santhosh.kumar@manipal.edu9741968550

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026