A COMPARATIVE STUDY OF TWO DIFFERENT LASERS IN TREATMENT OF FUNGAL NAIL INFECTION

A COMPARATIVE STUDY OF FRACTIONAL CO2 LASER VERSUS Q-SWITCHED ND-YAG LASER IN THE MANAGEMENT OF ONYCHOMYCOSIS

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/04/024710

Enrollment

Registered

2020-04-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L608- Other nail disorders

Interventions

Intervention1: FRACTIONAL CO2 LASER ON ONE ARM AND Q SWITCHED ND YAG ON SECOND ARM: a) Informed consent will be taken from individuals participating in the study. b) All the cases will be assessed cl

Eligibility

Inclusion criteria

Inclusion criteria: a) All consecutive patients over the age of 18 years of either gender reporting to the department of Dermatology, CHAF Bangalore with one or more toenail and/or fingernail fungal infections of the following types: distal subungual onychomycosis, proximal subungual onychomycosis, superficial white or black onychomycosis, mixed patterns or total dystrophic type onychomycosis. b) Diagnosis of Onychomycosis confirmed on demonstration of fungal hyphae on direct microscopy or fungal culture. c) Subjects should be willing and able to comply with all follow-up requirements d) Not on any medication for past 06 months for Onychomycosis.

Exclusion criteria

Exclusion criteria: a) Cases where KOH mount for fungal hyphae and fungal culture are negative. b) Patients who were on systemic or topical antifungals in the past three months. c) Nail disorders due to psoriasis, chronic eczema, lichen planus, bacterial infections, subungual hematoma, and non-onychomycosis causes of nail dystrophy. d) Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
TREATMENT OF NAIL FUNGAL INFECTION-l) Follow-up shall be performed at each visit at 4 weeks interval with assessment of clinical improvement using OSI score, photography and patient subjective assessment score. In addition to the above modalities, assessment will be done with mycological cultures and KOH mount after 16 weeks and 6 months from initiation of treatment. Analysis of the data will be carried out at 6 months after initiation of treatment .Timepoint: After 6weeks and 6 month of 1st sitting of laser treatment.	—

Measure

Time frame

TREATMENT OF NAIL FUNGAL INFECTION-l) Follow-up shall be performed at each visit at 4 weeks interval with assessment of clinical improvement using OSI score, photography and patient subjective assessment score. In addition to the above modalities, assessment will be done with mycological cultures and KOH mount after 16 weeks and 6 months from initiation of treatment. Analysis of the data will be carried out at 6 months after initiation of treatment .Timepoint: After 6weeks and 6 month of 1st sitting of laser treatment.

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Secondary

Measure	Time frame
REDUCTION IN QSI SCORETimepoint: 16 weeks and 6 months from initiation of treatment	—

Countries

India

Contacts

Public ContactDR GP CAPT SANDEEP ARORA

COMMAND HOSPITAL

aroraderma@gmail.com9910411635

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026