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Can a simple monitoring method predict worsening of brain injury towards Brain death

Near infrared spectroscopy as a predictor of evolution towards brain death following severe brain damage

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/04/024702
Enrollment
20
Registered
2020-04-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S062- Diffuse traumatic brain injury Health Condition 2: I609- Nontraumatic subarachnoid hemorrhage, unspecified

Interventions

None listed

Sponsors

Department of Neuroanaesthesia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients between the age of 15 and 70 admitted to the neurosurgery or neurology ICU with severe brain damage of known etiology- Subarachnoid hemorrhage (SAH), Traumatic brain injury (TBI), Intracerebral hemorrhage (ICH), Ischaemic stroke, comatose (GCS- 3 and FOUR score- zero)

Exclusion criteria

Exclusion criteria: 1. Refusal of consent by relative 2. CNS infections as the cause of coma/ Severe sepsis 3. Severe facial trauma including forehead scalp hematomas 4. Unevacuated SDH 5. Polytrauma â?? Lung injury and prior history of respiratory disease impeding ventilation and oxygenation 6. Prior history of cardiovascular disease

Design outcomes

Primary

MeasureTime frame
1. To observe the changes in regional cerebral oxygen saturation (rSO2) in patients following severe brain damage Timepoint: Hourly assessment

Secondary

MeasureTime frame
To assess the role of NIRS as a non-invasive ancillary method for the diagnosis of brain deathTimepoint: hourly assessment till brain death confirmed clinically

Countries

India

Contacts

Public ContactDR JAYANTH R SESHAN

ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI

girijarath.aiims@gmail.com9810602272

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026