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Curry leaf exact as mouth-rinse to prevent tooth decay

Ex vivo Evaluation of Glucosyltransferase Enzyme Inhibition And In vivo Analysis of Salivary pH and Buffering Capacity of Murraya koenigii Aqueous Extract as a Mouth rinse

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/04/024685
Enrollment
36
Registered
2020-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 0.5% Murraya koeinigii aqueous extract: Assessment of pH and buffering capacity of saliva immediately, 5 min, 10 min and 30 min after rinsing with 0.5% Murraya koeinigii aqueous extract

Sponsors

SRM Dental College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patients with ASA category I and 11 Patients having DMFT >5 with atleast one active carious lesion

Exclusion criteria

Exclusion criteria: Patients who used chemical anti plaque agents and mechanical debridements or were under antibiotics therapies. Patients with developmental anomalies. Mentally challenged patients. Patients with Xerostomia Patients undergoing orthodontic appliance therapy

Design outcomes

Primary

MeasureTime frame
Reduction in bacterial count in plaque and dental caries sample increase in pH of saliva Increase in buffering capacity of saliva and plaqueTimepoint: Immediately, 5 min , 10 min and 30 min.

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr C S Shobana

SRM Dental College

researchmaha@gmail.com9381018598

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026