A clinical trial comparing daily versus intermittent vitamin D supplementation in children with nephrotic syndrome

Randomized controlled trial to compare the effect of intermittent versus daily vitamin D supplementation on vitamin D status in children with nephrotic syndrome

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/04/024598

Enrollment

Registered

2020-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N049- Nephrotic syndrome with unspecified morphologic changes

Interventions

Intervention1: Intermittent vitamin D: Patients in this group will be given vitamin D in a dose of 60000IU given at an interval of 2 months for a period of 1 year Control Intervention1: Daily vitamin

Eligibility

Inclusion criteria

Inclusion criteria: Children in the age group of 20 ng/dL, shall be considered for enrolment in this trial.

Exclusion criteria

Exclusion criteria: 1. Age more than 14 years or 2. Refusal to give consent

Design outcomes

Primary

Measure	Time frame
Number of patients who remain vitamin D sufficient with 2 monthly vitamin D supplementationTimepoint: At 1 year of supplementation	—

Secondary

Measure	Time frame
Differences in bone health Timepoint: At 1 year follow up;Differences in serum levels of vitamin D, calcium, PTH and phosphorusTimepoint: At 1 year follow up;relapse frequency and rate of infectionTimepoint: 2 monthly for 1 year;Adverse effects of vitamin DTimepoint: 4 monthly for 1 year;changes in BMI and HeightTimepoint: 2 monthly for 1 year	—

Countries

India

Contacts

Public ContactShriyansh Kulshrestha

Jawaharlal Nehru Medical College, AMU

drkafzal@hotmail.com0571-2721182

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026