Health Condition 1: N049- Nephrotic syndrome with unspecified morphologic changes
Conditions
Interventions
Intervention1: daily low dose (0.15-0.25mg/kg): After allotment in this group the subjects will be given steroid in low dose daily 0.15mg/kg-0.25mg/kg(intervention group).
Control Intervention1: alter
Sponsors
Jawaharlal Nehru Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Children in the age group of 2-14 years diagnosed as SDNS/FRNS, who have at least 6 months follow up record at this centre, shall be considered for enrolment in this trial.
Exclusion criteria
Exclusion criteria: 1. Age at onset of nephrotic syndrome 10year. 2. Use of alternative treatment other than prednisolone 3. Biopsy showing pathology other than MCNS. 4. Secondary nephrotic syndrome. 5. Late steroid resistance. 6. Residing >100km from the centre or unwilling to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relapse frequency.Timepoint: At Enrolment,At 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. safety (side effect of corticosteroids) 2. Time to first relapse 3. Proportion of patients relapse-free 4. Cumulative steroid dose used 5. Infection episodes 6. Need for alternative medications.Timepoint: 3 monthly during 1 year followup | — |
Countries
India
Contacts
Public ContactZulquarnain
Jawaharlal Nehru Medical College,AMU
Outcome results
None listed