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The study is to identify whether adding midazolam before propofol induction helps in smooth insertion of Laryngeal mask airway.

Effect of Midazolam in aiding the insertion of Laryngeal mask airway during propofol induction - a randomized double blind trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/04/024572
Enrollment
58
Registered
2020-04-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: R688- Other general symptoms and signs

Interventions

Intervention1: Effect of midazolam in lowering the dose requirement of propofol in LMA insertion in adults : Group A patients will be given 0.05ml/kg Normal saline. Group B patients will be given 0.05

Sponsors

JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION RESEARCH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 60 years in ASA Physical status 1 and 2 undergoing elective surgeries lasting not more than 2 hours requiring general anesthesia in JIPMER

Exclusion criteria

Exclusion criteria: Neuromuscular diseases Presence of pharyngeal diseases A known case of difficult airway Risk of aspiration Lung pathology Body mass index >35 Surgeries requiring post-operative NPO >24 hours

Design outcomes

Primary

MeasureTime frame
To compare the effect of Midazolam and Normal saline in reducing the dose requirement of propofol in LMA insertion Timepoint: Loss of eyelash reflex and loss of jaw muscle tone will be the end point of propofol infusion

Secondary

MeasureTime frame
Comparision of Jaw relaxation Comparision of Hemodynamic stability Comparision of Post-operative complications Timepoint: LMA insertion score Mouth opening - 0/1/2 Ease of insertion â?? 0/1/2 Swallowing â?? 0/1/2 Coughing â?? 0/1/2 Laryngospasm â?? 0/1/2 Movements â?? 0/1/2 Measuring Heart rate and Blood pressure on the day of preop assessment ,before induction,just after inserting LMA, at 1min, 2min, 5min and 10min Foreign body sensation, dysphagia, dysphonia, hoarseness and others assessed at 1 and 24hours post surgery.

Countries

India

Contacts

Public ContactDr M V S Satya Prakash

JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION & RESEARCH,

munaganuri1975@yahoo.co.in9786184626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026