Sonophoresis in the treatment of periodontitis.

A Comparative study to evaluate the effectiveness of sonophoresis as an adjunct to non-surgical periodontal therapy.

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/04/024565

Enrollment

Registered

2020-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: R898- Other abnormal findings in specimens from other organs, systems and tissues

Interventions

Intervention1: Sonophoresis: 2% Metronidazole gel sonophoresis, scaling and root planing Control Intervention1: Topical metronidazole: 2% topical metronidazole, scaling and root planing, sham sonophor

Eligibility

Inclusion criteria

Inclusion criteria: Chronic periodontitis (AAP 1999 classification) Probing depth of 5mm or more in more than 30% sites Systemically healthy No antibiotic useage in the last 6 months Did not undergo periodontal therapy in the last 6 months Non-pregnant, not lactating women

Exclusion criteria

Exclusion criteria: Patients with systemic diseases Patients allergic to metronidazole

Design outcomes

Primary

Measure	Time frame
Periodontal probing depth in mm, MMP-8 levels in saliva using ELISA, bacterial colony forming units (CFU)Timepoint: baseline, 1 month post treatment	—

Secondary

Measure	Time frame
Bleeding indexTimepoint: Baseline, 1 month post treatment;Clinical attachment levelTimepoint: Baseline, 1 month post treatment;Plaque indexTimepoint: Baseline and 1 month post treatment	—

Countries

India

Contacts

Public ContactDipika Inbasekaran

Saveetha Instiyute of medical and technical sciences,

profndj@yahoo.com8828486379

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026