Comparative Evaluation Of two different drugs With Peripheral Nerve Blocks For Split Skin Grafting From Lower Limbs In Adults

Comparative Evaluation Of Combined Use Of Intravenous Dexmedetomidine-Ketamine With Dexmedetomidine Alone With Peripheral Nerve Blocks For Split Skin Grafting From Lower Limbs In Adults

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/04/024559

Enrollment

Registered

2020-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: X16- Contact with hot heating appliances, radiators and pipes

Interventions

Intervention1: Combined use of intravenous Dexmedetomidine-ketamine with Dexmedetomidine alone with peripheral nerve block in two different groups: Group DK will receive intravenous Dexmedetomidine-ke

Eligibility

Inclusion criteria

Inclusion criteria: 1) Adults aged between 18-65 years undergoing split skin grafting from anterolateral aspect of thigh in supine position when the area of harvesting/donor site is less than 5 percent 2) ASA grade 1

Exclusion criteria

Exclusion criteria: Patients with co-morbidities like hypertension, diabetes mellitus,sepsis, difficult airway or any other sysyetmic disorder

Design outcomes

Primary

Measure	Time frame
To study and compare the role of combined use of Intravenous Dexmedetomidine-Ketamine with Dexmedetomidine alone with peripheral nerve block for sedation-analgesia in split skin Grafting From Lower Limbs In Adults using Ramsay Sedation ScoreTimepoint: Every 5 minutes vital monitoring intraoperatively and outcome assessment by ramsay sedation score intraoperatively	—

Secondary

Measure	Time frame
To compare the haemodynamic changes Associated with the combined use of intravenous Dexmedetomidine-ketamine with Dexmedetomidine alone for sedation-analgesia in adultsTimepoint: Peri-operative	—

Countries

India

Contacts

Public ContactSudhir kumar

Vardhman Mahavir Medical College and Safdarjang Hospital

Ameetaas@yahoo.com9811201585

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026