Health Condition 1: D50-D89- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Healthy adult patients between 25-70 years. 2.Individuals with mild to severe periodontitis
Exclusion criteria
Exclusion criteria: 1.smoking >20 cigarettes/day 2.uncontrolled diabetes 3.immunosuppression (pathological or drug-induced) 4.current therapy with antiresorptive drugs (bisphosphonates) 5.pregnancy and breastfeeding 6.patients in need of antibiotic therapy or treatment with antibiotic in the previous month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Following clinical parameters will be recorded at baseline for healthy group and periodontitis group:Plaque index (Silness and Loe 1967),Gingival index (GI),(Loe and Silness 1963),Probing depth,Clinical Attachment level and Serum IL-8 level. Timepoint: BASELINE | — |
Secondary
| Measure | Time frame |
|---|---|
| Following clinical parameters will be recorded after 20 days only for experimental group:Plaque index (Silness and Loe 1967),Gingival index (GI),(Loe and Silness 1963),Probing depth,Clinical Attachment level and Serum IL-8 level Timepoint: 20 days | — |
Countries
India
Contacts
SDM College of dental science and hospital