None listed
Conditions
Interventions
None listed
Sponsors
Wellcome Trust DBT India Alliance
Eligibility
Inclusion criteria
Inclusion criteria: Normal BMI between18.5 to 25 kg/m²; or either normal or low BMI ( <18 kg/m2) for the group with EED
Exclusion criteria
Exclusion criteria: 1. History of smoking or taking other leisure drugs 2. Consumption of alcohol in the previous 24 hours 3. History of antibiotic usage 4 weeks prior to the study 4. On iron supplementation therapy (3 months) 5. On medication such as NSAIDâ??s, proton pump inhibitors or H2 blockers 2 days prior to and on the study day 6. Participation in any nutritional study in the last 6 months 7. History of food allergy, specifically to milk 8. Diagnosed with chronic medical or surgical illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main aim of this study is to compare the protein digestion and amino acid absorption in adults with and without EED.Timepoint: Digestibility calculation will be performed from 4 time points starting from the 5th hour to 8th hour and will be compared between the adult EED and without EED group | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare true ileal indispensable amino acid digestibility of goat milk and allo-isoleucine absorption between adults with and without EED To compare the digestibility and absorption indices obtained for adults with and without EED to plasma/fecal intestinal inflammatory biomarkers and fecal elastase-1 Timepoint: For the absorption study 4 time points of plasma enrichment of alloisoleucine will be used to calculate the absorption index For the inflammatory biomarkers and fecal elastase-1, 1 time point stool sample will be taken and compared between the groups | — |
Countries
India
Contacts
Public ContactNirupama Shivakumar
st. Johns National Academy of Health Sciences
Outcome results
None listed