Health Condition 1: I083- Combined rheumatic disorders of mitral, aortic and tricuspid valves
Conditions
Interventions
Intervention1: 1mg/kg Injection Amiadarone: 1mg/kg Injection Amiadarone givenalong with cardioplegia during cardiopulmonary bypass after cross clamp application study end after cross clamp release
Con
Sponsors
VMMC AND SAFDARJUNG HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: All adult patient with valvular heart surgery/cabg with atrial fibrillation.
Exclusion criteria
Exclusion criteria: Contraindications to amiodarone (sick sinus syndrome, atrioventricular conduction abnormalities, thyroid disease, interstitial lung disorders, renal or liver disease) b) Need of concomitant cardiac surgical procedure c)Emergency operation d)Pretreatment with digoxin or amiodarone .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 To investigate whether prophylactic amiodarone infusion prevents re-emergent of atrial fibrillation after aortic cross-clamp removed in patients with atrial fibrillation undergoing open cardiac surgery. 3.2To study the hemodynamic response of amiadarone after clamp off. 3.3Ease of separation from cardiopulmonary bypass. Timepoint: Immediately after aortic cross-clamp release and end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| .To study the hemodynamic response of amiadarone after clamp off. .Ease of separation from cardiopulmonary bypass Timepoint: END OF BYPASS TILL DISCHARGE FROM ICU | — |
Countries
India
Contacts
Public ContactARIN CHOUDHURY
VMMC AND SAFDARDUNG HOSPITAL
Outcome results
None listed