Comparison of two different doses of fentanyl and lignocaine in reducing agitation and hyperactivity from general anaesthesia in ENT surgeries

Comparison of two different doses of fentanyl and lignocaine in reducing emergence agitation during extubation in ENT surgeries- A Prospective Randomised Double blind study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/04/024488

Enrollment

169

Registered

2020-04-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H748- Other specified disorders of middle ear and mastoid

Interventions

Intervention1: Reducing emergence agitation before extubation: Emergence agitation causes very real distress to the patients after extubation.It can be prevented by using intravenous Fentanyl(1mcg/kg)

Eligibility

Inclusion criteria

Inclusion criteria: All genders,age 20-70years,all ear nose throat surgeries,surgical duration more than 1 hours less than 4 hours,ASA1-2

Exclusion criteria

Exclusion criteria: All surgeries apart from ear,nose,throat surgeries,pediatric age group,age over 70 years,patients on epidural infusion,surgery time less than 1 hour or more than 4 hours,all emergency surgeries

Design outcomes

Primary

Measure	Time frame
Grading of Emergence AgitationTimepoint: Agitation will be assessed every minute from drug administration to discharge from the operating room	—

Secondary

Measure	Time frame
Sedation Grading System Postoperative nausea and vomitingTimepoint: Time between discharge from operating room to discharge from Postanaesthetic Care Unit	—

Countries

India

Contacts

Public ContactSivasankari G

Sri Ramachandra Institute of Higher Education and Research

rampond@gmail.com9380537411

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026