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Comparision of two drugs i.e Ketamine and Dexmedetomidine for providing sufficient pain relief in patients undergoing surgery for weight reduction

Comparision of ketamine and dexmedetomidine infusions as non opioid anaesthetic technique during laparoscopic bariatric surgery : A randomised clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/04/024441
Enrollment
50
Registered
2020-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E00-E89- Endocrine, nutritional and metabolic diseases

Interventions

Intervention1: comparing safety and efficacy of ketamine and dexmedetomidine as effective anaesthetic technique: Administering of ketamine in one group as intravenous infusion at dose of 0.5 mg bolus

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists (ASA) classification II & III undergoing elective bariatric surgery

Exclusion criteria

Exclusion criteria: 1. Patients refusal to participate in the study 2. An allergy to study drugs. 3. A history of alcohol or drug abuse 4. Clinically significant neurologic , cardiovascular , renal , hepatic or gastrointestinal disorder. 5. Received an opioid analgesic medication within a 24 hour period before surgery.

Design outcomes

Primary

MeasureTime frame
Primary outcome data will be Haemodynamics i.e heart rate at induction(T1) and half hourly thereafter, NIBP ( SBP, DBP, MAP) at induction (T1) and half hourly thereafter.Timepoint: Primary outcome data will be Haemodynamics i.e heart rate at induction(T1) and half hourly thereafter, NIBP ( SBP, DBP, MAP) at induction (T1) and half hourly thereafter.

Secondary

MeasureTime frame
1. Time to extubate. 2. Pain in terms of VAS(Visual analog score) 3. Discharge from PACU (Post anaesthesia care unit) on Aldrete score 4. Discharge from ward 5. Patient satisfactionTimepoint: Immediate post operative pain (t1) and half hourly thereafter

Countries

India

Contacts

Public ContactJasmin Bulbul

All India Institute Of Medical Science New Delhi

dilipshende@gmail.com8800377697

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026