Health Condition 1: E43- Unspecified severe protein-caloriemalnutrition
Conditions
Interventions
Intervention1: Vitamin D3: 60000IU Vitamin D3 orally weekly for 6 week along with standard therapy for SAM (except vitamin D ) for 2 weeks.
Control Intervention1: SAM supplements: SAM supplements is g
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: Children with severe acute malnutrition with medical complication with vitamin D3 level less than 20ng/ml.
Exclusion criteria
Exclusion criteria: Children undergoing treatment for vitamin D deficiency(Rickets) or received vitamin D therapy in the last 3 months. Children suffering from chronic systemic diseases ie. secondary cases of SAM(any chronic Renal, cardiac, hepatic, neurological or developmental and major anomalies/surgical cases. Children suffering from known malabsorption disease like celiac disease, malabsorption syndromes, cardiac failure. Children suffering from known metabolic bone disease. Children on anticonvulsants or any other medication interfere with cytochrome P450 activities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of children with mean weight for height Z score more than 0.5 SD from base line at the end of 8 week in both groups.Timepoint: 8 week | — |
Secondary
| Measure | Time frame |
|---|---|
| Propotion of children with weight gain more than 15% from base at the end of 8 weeks in both groups. Proportion of children having recurrent infections and severe infections at the end of 8 weeks. Level of vitamin D in both groups at the end of 8 week.Timepoint: 8 week | — |
Countries
India
Contacts
Public ContactSrikanta Basu
kalawati saran children hospital
Outcome results
None listed