FindTrial
Sign In

A Study to find markers in blood and cerebrospinal fluid to help diagnose tuberculosis of the brain

Identification of Biomarkers for Central Nervous System Tuberculosis - CNSTB STUDY

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/04/024423
Enrollment
216
Registered
2020-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A179- Tuberculosis of nervous system, unspecified

Interventions

None listed

Sponsors

University Hospital Frankfurt
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Clinically suspected Central Nervous System Tuberculosis

Exclusion criteria

Exclusion criteria: • Informed consent not given • Lumbar puncture not possible/not performed before start of treatment

Design outcomes

Primary

MeasureTime frame
â?¢ Diagnostic accuracy (sensitivity, specificity, positive predictive value, negative predictive value) of biomarkers for differentiating CNS Tb and clinically relevant differential diagnosis (sarcoidosis, lymphoma, other infectious cause) Timepoint: Baseline ( Date of Patient Enrollment ) and follow-up at 6 months—

Secondary

MeasureTime frame
â?¢ Diagnostic accuracy (sensitivity, specificity, positive predictive value, negative predictive value) of biomarkers at 6 month follow up for treatment success and clinical outcomeTimepoint: Baseline ( Date of Patient Enrollment ) and follow-up at 6 months—

Countries

India

Contacts

Public ContactDr Ivy Anne Sebastian

Christian Medical College and Hospital, Ludhiana

jeyarajpandian@hotmail.com9915784750

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026