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A study to evaluate changes in normal clotting (process by which blood changes from a liquid to a gel, forming a blood clot) test and advanced clotting (process by which blood changes from a liquid to a gel, forming a blood clot) test in patients undergoing liver surgeries

Prospective PeriOperative study Evaluating Routine Coagulation versus Thromboelastography for Liver resections (More Than Three Segments) (PORTAL Trial) - PORTAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/04/024419
Enrollment
25
Registered
2020-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C22- Malignant neoplasm of liver and intrahepatic bile ducts

Interventions

Intervention1: TEG and routine coagulation profiles: Routine induction at the discretion of OT anaesthetists will be done. After arterial line is secured, first sample will be collected and subsequent

Sponsors

Tata Memorial Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. 25 adults ( >18yrs) cases 2. Major hepatic resection >3 segments

Exclusion criteria

Exclusion criteria: 1. On therapeutic doses of thromboprophylaxis 2. Abnormal coagulation or platelets 3. Any known coagulation disorder 4. Refusal of consent

Design outcomes

Primary

MeasureTime frame
The primary aim of our study is to study the serial changes of conventional coagulational tests and thromboelastography and their correlation during perioperative period in patients undergoing major liver resection (more than 3 segments) at multiple timepointsTimepoint: 1. Preincision 2. Intraoperative (based at discretion of OT anaesthetists)) 3. Postoperative 4. 48 hrs 5. 5th postop day—

Secondary

MeasureTime frame
1. To record the incidence of prevention of transfusion of blood products (Fresh frozen plasma, Cryoprecipitate, platelets) (In case when INR being more than 1.5 and TEG is normal) 2. Incidence of complications like bleeding, deep vein thrombosis, epidural hematoma Timepoint: 1. Preincision 2. Intraoperative (based at discretion of OT anaesthetists)) 3. Postoperative 4. 48 hrs 5. 5th postop day—

Countries

India

Contacts

Public ContactDr Vignesh B

Tata Memorial Hospital

rambulkar@hotmail.com9821790448

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026