None listed
Conditions
Interventions
Intervention1: HCQS -MIMS Regimen: 300 mg daily x 1 wk followed by 300 mg weekly
Intervention2: Hydroxychloroquine: 300 mg daily x 7 days followed by 300 mg weekly x 7 weeks
Control Intervention1: Hyd
Sponsors
Dr Remesh Bhasi
Aster MIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1. Moderate to high risk of exposure to infected patients during the study period. 2. Healthy at the time of enrolment without any symptoms suggestive of any viral infection.
Exclusion criteria
Exclusion criteria: 1. History of known allergy to Hydro ChloroQuine(HCQ) or Chloroquine 2. Known contraindications for HCQ or Chloroquine including Retinopathy, known Cardiac disease like Dysarrythmias, and G6PD deficiency. 3. Pregnancy and Lactation 4. History of recent (within one month) International travel. 5. Features of any ongoing infection including COVID-19
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infected Non infectedTimepoint: Time to clinical improvement | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality, percentage of patients who had clinical improvement, oxygen support days, Mechanical ventilation, ICU stay days, total hospital stay, clinical score, MODs plus or minusTimepoint: 28 days mortality 7 day and 14 day clinical score and all others at the time of discharge | — |
Countries
India
Contacts
Public ContactDr Remesh Bhasi
Aster Malabar Institute of Medical Sceinces
Outcome results
None listed