Health Condition 1: I10- Essential (primary) hypertension
Conditions
Interventions
Control Intervention1: anti-hypertensive drug: Telmisartan
Control Intervention2: Anti-hypertensive drug: Tab. Benidipine 4mg OD PO 3months
Control Intervention3: Anti-hypertensive drug: Tab. Amlodipi
Sponsors
AIIMS Patna
Eligibility
Inclusion criteria
Inclusion criteria: 1) Newly diagnosed hypertensive patient. 2) Age: >=30 years to 3) BMI: >18.5 to 4) Sex: Both. 5) Systolic Blood Pressure: >=140 to 6) Diastolic Blood Pressure: >=90 to
Exclusion criteria
Exclusion criteria: 1) Age: =60yrs. 2) BMI: 30 kg/m2. 3) Patients diagnosed with secondary hypertension. 4) Patients with renal disease (serum creatinine >1.2). 5) Patients with any history of drug allergies with anti-hypertensive agents. 6) Patients on any other anti-hypertensive drugs (ACEI/DIURETICS/BETA-BLOCKERS). 7) Patients with liver diseases (ALT/AST 8) Patients with pre-existing pedal edema, hypoproteinemia, and Nephrotic syndrome. 9) Patients with any other chronic illness (Diabetes, Rheumatoid arthritis, Tuberculosis). 10) On long term NSAID and steroids. 11) Patients with unsound mind and drug addicts. 12) Pregnant and lactating women. 13) Patient not willing to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy-B.P(Day 1, day 15, 1 monthand at 3rd month) Safety -Lipid profile,LFT day 1 and after 3month) Safety-ADRTimepoint: one year | — |
Secondary
| Measure | Time frame |
|---|---|
| cost- effectiveness Quality of life at Day 1 and after 3 monthsTimepoint: one year;effect of drugs on lipid profile, liver function test and renal function test at Day 1 and at 3rd month.Timepoint: one year | — |
Countries
India
Contacts
Public ContactDr Aakanksha Priya
MBBS, MD
Outcome results
None listed