Comparison of Spirulina Gel as Local Drug Delivery Agent in Surgical Management Of vertical Defects in Chronic Periodontitis.

Comparative Evaluation of Effectiveness of Spirulina Gel as Local Drug Delivery Agent In Surgical Management Of Intrabony Defects in Chronic Periodontitis â?? A Randomized Control Trial.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/03/024323

Enrollment

Registered

2020-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Spirulina gel: Patients receiving Spirulina gel in surgical management of intrabony defects in chronic periodontitis. Dose:Spirulina 40mg per 1ml of gel. Frequency: After scaling and ro

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria:- 1) systemically healthy patients with intra bony defects. 2) Male and female patients of age groups 25 to 65 years. 3) Periodontal lesions with pocket probing depth (PPD) >5 mm. 4) Intrabony defect > 3 mm. 5) Patients ready to comply fully and willing to give consent for the final evaluation. 6) Patients having ability to maintain optimum oral hygiene.

Exclusion criteria

Exclusion criteria: Exclusion Criteria:- 1) Patients with systemic diseases that contraindicates the surgery, immune compromised patients or having taken antibiotics with in preceding 3 months. 2) Third molar region. 3)Patients on anticoagulants and/or with blood diseases. 4)Pregnant or lactating females. 5) Patients undergoing orthodontic treatment. 6) Those who have undergone periodontal surgical treatment with in the last 6 months

Design outcomes

Primary

Measure	Time frame
To evaluate and compare clinical parameter ((1) Probing Pocket Depth (PPD) (2) Gingival Recession (GR) (3) Clinical Attachment Level (CAL) (4) Radiographic Bone Defect Fill )radiographical the bone defect fill with or without Spirulina gel as local drug delivery in regenerative treatment of intra bony defects in chronic periodontitis. Timepoint: Base line 1 Â½ months 3 months 6 months (3months post surgical) 12 months (9months post surgical)	—

Measure

Time frame

To evaluate and compare clinical parameter ((1) Probing Pocket Depth (PPD) (2) Gingival Recession (GR) (3) Clinical Attachment Level (CAL) (4) Radiographic Bone Defect Fill )radiographical the bone defect fill with or without Spirulina gel as local drug delivery in regenerative treatment of intra bony defects in chronic periodontitis. Timepoint: Base line 1 Â½ months 3 months 6 months (3months post surgical) 12 months (9months post surgical)

—

Secondary

Measure	Time frame
To evaluate and compare clinical parameters ((1) Probing Pocket Depth (PPD) (2) Gingival Recession (GR) (3) Clinical Attachment Level (CAL) (4) Radiographic Bone Defect Fill ) with or without using Spirulina gel as a local drug delivery, adjunct to scaling and root planning in the treatment of intra bony defects in chronic periodontitis. Timepoint: Base line 1 Â½ months 3 months 6 months (3months post surgical) 12 months (9months post surgical)	—

Measure

Time frame

To evaluate and compare clinical parameters ((1) Probing Pocket Depth (PPD) (2) Gingival Recession (GR) (3) Clinical Attachment Level (CAL) (4) Radiographic Bone Defect Fill ) with or without using Spirulina gel as a local drug delivery, adjunct to scaling and root planning in the treatment of intra bony defects in chronic periodontitis. Timepoint: Base line 1 Â½ months 3 months 6 months (3months post surgical) 12 months (9months post surgical)

—

Countries

India

Contacts

Public ContactDr Mayuri Rajiv Ghike

Government Dental College,Nagpur

drmbphadnaik@gmail.com9422203650

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026