Comparison Of Ketamine Versus Magesium Sulfate Nebulization For Attenuation Of Postoperative Sore Throat in Patients Undergoing Nasal Surgeries

Ketamine Nebulization Versus Magnesium Sulfate Nebulization For Attenuation Of Postoperative Sore Throat In Patients Undergoing Nasal Surgeries- A Prospective Randomised Double Blinded Sudy

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/03/024299

Enrollment

128

Registered

2020-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J329- Chronic sinusitis, unspecified Health Condition 2: J342- Deviated nasal septum

Interventions

Intervention1: Nebulization: Pre operative nebulization, 10 minutes prior induction of Anesthesia Control Intervention1: ketamine: Pre operative nebulization with 50mg Ketamine with 4 ml normal saline

Eligibility

Inclusion criteria

Inclusion criteria: Elective Nasal Surgeries, American Standard Association Class 1 And 2, Patients with Mallampatti grade 1 and 2

Exclusion criteria

Exclusion criteria: Patient refusal, Anticipated difficult airway, Patients with reactive airway disease, Patients with difficult airway who needed more than 3 attempts at intubation

Design outcomes

Primary

Measure	Time frame
Attenuation Of Postoperative Sore ThroatTimepoint: Post extubation: 15 minutes ,30 minutes,1st hour, 2nd hour, 6th hour, 12th hour, 24th hour	—

Secondary

Measure	Time frame
Presence of cough Hoarseness of voiceTimepoint: Post extubation: 15 minutes, 30 minutes, 1st hour, 2nd hour, 6th hour, 12th hour, 24th hour	—

Countries

India

Contacts

Public ContactAKILANDESWARI M

Sri Ramachandra Institute Of Higher Education And Research

sathya26692@gmail.com9952923887

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026