Comparison of efficacy of radiofrequency ablation and sclerotherapy for the closure of perforator veins in varicose veins.

A single center randomized control trial to compare the efficacy of radiofrequency ablation with that of ultrasound guided foam sclerotherapy (polidocanol) for incompetent perforators in patients with varicose vein.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/03/024257

Enrollment

140

Registered

2020-03-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I832- Varicose veins of lower extremities with both ulcer and inflammation

Interventions

Intervention1: Foam Sclerotherapy (Polidcanol): Foam Sclerotherapy prepared using Tessari Method (mixing polidocanol and air in 1:4 proportion). 0.5 - 1ml of foam sclerosant in an superficial varicosi

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with isolated incompetent perforators 2. Post-GSV ablation patients having incompetent perforators

Exclusion criteria

Exclusion criteria: 1. Patients having deep venous thrombosis. 2. Patients with contraindication for the therapy; allergic to contrast media or sclerosant.

Design outcomes

Primary

Measure	Time frame
1.Obliteration of perforators within 48 hours, 3,6 and 12 months follow up on Doppler evaluation 2.Venous clinical severity score (VCSS), baseline and at 12 months Timepoint: 48 hours, 3,6 and 12 months	—

Secondary

Measure	Time frame
Incidence of post-procedure ecchymosis, pain, discomfort, DVT, pulmonary embolism.Timepoint: 6 and 12months	—

Countries

India

Contacts

Public ContactDrAmit Deshpande

AIIMS, New Delhi

sanjeevradio@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026