Evaluation of post-operative swelling, pain, difficulty in mouth opening of dexamethasonized lignocaine (TWIN MIX) versus intravenous dexamethasone after the removal of impacted mandibular third molar- A split mouth study

Evaluation of Post-Operative Sequelae of TWIN MIX Versus Intravenous Dexamethasone After The Removal of Impacted Mandibular Third Molar- A Split Mouth Study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/03/024239

Enrollment

Registered

2020-03-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: TWIN MIX: Dose- 1.8ml 2% lignocaine with 1:200000 epinephrine mixed with 1 ml dexamethasone inj 4mg given pre-operatively Route- intra-oral given as inferior alveolar nerve block du

Eligibility

Inclusion criteria

Inclusion criteria: 1) Individuals who are willing to participate in the study 2) Individuals with bilaterally impacted teeth which falls under same Pell and Gregory classification. 3) Male and female patients of age 18-55 years. 4) Individuals under ASA I

Exclusion criteria

Exclusion criteria: 1)Reported allergy to any of the products used in the study 2)Individuals with any uncontrolled systemic disease 3)Individuals with severe acute infections 4)Individuals with chronic substance abuse 5)An unwillingness to participate in the study 6)Pregnant or lactating females

Design outcomes

Primary

Measure	Time frame
1)To assess the effect of preoperative injection of twin mix as a inferior alveolar nerve block on reducing facial swelling after the surgical removal of impacted mandibular third molars 2)To evaluate the interincisal mouth opening. 3)To assess postoperative pain that will occur following surgery.Timepoint: pre-operatively and 1 hour, 36 hours, 168 hours post operatively	—

Secondary

Measure	Time frame
To evaluate the latency and duration of â??Twin mixâ?? intraoperatively The need to re-anesthetize the surgical site will also be recorded. Timepoint: Latency measured as the time elapse from full needle withdrawal until the onset of subjective signs of anesthesia will be recorded. The duration of anesthesia (1 hour post -injection) is in turn recorded as the time from initial patient perception of the anesthetic effect to the moment in which the effect began to fade .	—

Measure

Time frame

To evaluate the latency and duration of â??Twin mixâ?? intraoperatively The need to re-anesthetize the surgical site will also be recorded. Timepoint: Latency measured as the time elapse from full needle withdrawal until the onset of subjective signs of anesthesia will be recorded. The duration of anesthesia (1 hour post -injection) is in turn recorded as the time from initial patient perception of the anesthetic effect to the moment in which the effect began to fade .

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Countries

India

Contacts

Public ContactDr Aarathy P T

P M S college of dental science and research

nikhilmkurien@gmail.com9496108601

Outcome results