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To study the effect of High Molecular Weight Hyaluronic Acid injection when given directly into Knee joint in patients with Osteoarthritis Knee

Study of efficacy of single dose high molecular weight intra-articular hyaluronic acid injection in osteoarthritis knee

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/024224
Enrollment
44
Registered
2020-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Single dose high molecular weight intra articular hyaluronic acid injection in osteoarthritis knee: Single dose intra articular injection of High Molecular weight hyaluronic acid 90 mg/

Sponsors

VMMC and Safdarjung hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients of either gender diagnosed with primary OA knee of tibiofemoral joint as defined by ACR cliniucal and radiographic criteria Radiological grade II and III ofknee OA according to Kellgren-Lawrence classification Body Mass Index <40

Exclusion criteria

Exclusion criteria: history of bleeding disorders ipsilateral cruciate or collateral ligament injury intra articular treatment with any product or joint lavage any arthroscopic procedure within prior six months any knee surgery within prior 12 months any overlying skin infection venous or lymphatic stasis on anticoagulation therapy in previous 7 days

Design outcomes

Primary

MeasureTime frame
To study the clinical outcome in OA knee following intra articular hyaluronic acid injection using VAS scoring system and KOOSTimepoint: 3 months after injection—

Secondary

MeasureTime frame
To assess the cartilage thickness pre and post hyaluronic acid injection by MRITimepoint: 3 months—

Countries

India

Contacts

Public ContactAnjana Babu

VMMC and Safdarjung hospital

anjanab27@gmail.com9947925665

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026