Health Condition 1: N819- Female genital prolapse, unspecified
Conditions
Interventions
Intervention1: Normal saline: Normal saline 60 ml by slow IV injection at @of 1 ml/ min, and throughout the operation irrigation will be done by 60 ml of NS by microdrip
Intervention2: Tranexamic aci
Sponsors
Dr Sudarshan Dash
Dr Debasis Bsisoi
Eligibility
Inclusion criteria
Inclusion criteria: 1.patients of age > 18 years undergoing vaginal hysterectomy under spinal anesthesia with or without bilateral salpingooophorectomy (BSO) due to myoma, menorrhagia, metrorrhagia, chronic pelvic pain, and endometrial hyperplasia giving written informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients undergoing abdominal or laparoscopic hysterectomy 2.Patients undergoing vaginal hysterectomy under general anesthesia 3.Patients with cardiac, hepatic, renal, or thromboembolic disease 4. Patients with pelvic endometriosis and adnexal mass 5.Patients with endometrial or cervical cancer 6.Patients using Anticoagulants ,NSAIDs, antiplatelets, contraceptive medications, hormone-containing medications, patients on medications for DVT prophylaxis 7. Patients with history of allergy to tranexamic acid.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To estimate intraoperative, postoperative, and total blood loss (ml) in women undergoing vaginal hysterectomy in each groupsTimepoint: day 2 i.e. 24 hours post surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To estimate need for blood transfusion, operative time, and period for hospitalization, hemoglobin concentration 24 h postoperative, and the change in hemoglobin concentration pre- and postoperative in women undergoing vaginal hysterectomy in each group.Timepoint: 24 hours post surgery | — |
Countries
India
Contacts
Public ContactDr Sudarshan Dash
Kalinga Institute of Medical Sciences, Bhubaneswar
Outcome results
None listed