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A study to find the duration of pain relief provided by Morphine and Dexmedetomidine when used along with bupivacaine given in the spinal region for lower limb fractures surgeries.

A Randomised Control Trial To Analyse The Duration Of Analgesia Of Intrathecal Morphine And Dexmedetomidine As Adjuvants To Bupivacaine In Subarachnoid Block For Lower Limb Orthopaedic Surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/024199
Enrollment
70
Registered
2020-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: M979- Periprosthetic fracture around unspecified internal prosthetic joint

Interventions

Intervention1: Intrathecal dexmedetomidine as adjuvant to bupivacaine in subarachnoid block: To analyse the duration of analgesia of intrathecal dexmedetomidine 5microgram as adjuvant to bupivacain

Sponsors

SRM medical College Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade I-II

Exclusion criteria

Exclusion criteria: 1. The presence of absolute contraindication to spinal or epidural technique 2. Known case of allergic airway disorders 3. Failed spinal. 4. Height 6 feet 5. BMI >30 6. Cognitive or psychiatric disturbances 7. Spinal deformities 8. Patients who have undergone spine surgeries in the past. 9. Surgery duration extending beyond 150 minutes

Design outcomes

Primary

MeasureTime frame
To compare the duration of analgesia.Timepoint: 24hours after spinal injection—

Secondary

MeasureTime frame
1. The motor and sensory onset timeTimepoint: minutes;2. HemodynamicsTimepoint: beats/minute, rate/minute, percentage,mm/hg;3. Two point regressionTimepoint: score;4. SedationTimepoint: score;5. Quantity of rescue analgesicsTimepoint: 24 hours after administration of drug;6. Incidence of side effects ( bradycardia, hypotension,nausea,vomiting,pruritis,respiratory depression) Timepoint: for 24 hours after drug administration—

Countries

India

Contacts

Public ContactBalaji Ramamurthy

Srm Medical College Hospital and Research Centre

aarbee79@gmail.com9047019047

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026