Health Condition 1: M059- Rheumatoid arthritis with rheumatoid factor, unspecified Health Condition 2: M498- Spondylopathy in diseases classified elsewhere Health Condition 3: K519- Ulcerative colitis, unspecified Health Condition 4: M469- Unspecified inflammatory spondylopathy
Conditions
Interventions
Intervention1: Sulfasalazine tablets: sulfasalazine tablets 1g will be given twice daily will be given orally for 3 months
Control Intervention1: methotrexate: methotrexate 10 mg tablets will be given
Sponsors
Dr Debasis Bisoi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male patient aged 18-60 years diagnosed with in male patients with spondyloarthritis , rheumatoid arthritis, ulcerative colitis. 2. Patient giving written informed consent and willing to comply with study related procedures
Exclusion criteria
Exclusion criteria: 1. Patients diagnosed to have primary infertility. 2. Patient having structural deformity of the male genitourinary system. 3. Patient with inguinal hernia, hydrocele. 4. Patient having H/O hypersensitivity or drug allergy. 5. Patients with impaired hepatic or renal function. 6. Patient with ischemic heart disease or heart failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Change in seminal parameters from the baseline at the end of the study i.e. 3 months in patients with spondyloarthritis , rheumatoid arthritis, ulcerative colitis. 2. Adverse reactions reported in patients with spondyloarthritis , rheumatoid arthritis, ulcerative colitis Timepoint: at baseline and at 90 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in complete blood count parameters from baseline to the end of study in patients with spondyloarthritis , rheumatoid arthritis, ulcerative colitis .Timepoint: baseline and at 3 months | — |
Countries
India
Contacts
Public ContactDr Debasis Bisoi
Kalinga Institute of Medical Sciences, Bhubaneswar
Outcome results
None listed