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Antibiotics in Treatment of Chronic periodontitis

Evaluation of Cefixime and Ofloxacin as an adjunct to scaling and root planing in the treatment of generalized chronic periodontitis - A clinicomicrobiological study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/024163
Enrollment
32
Registered
2020-03-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Cefixime-Ofloxacin adjunct to Sclaing and root planing: It is a combination drug of Cefixime(200mg) and ofloxacin(200mg). Both are antibiotics and will given twice daily for 5 days. Con

Sponsors

Sri Hasanamba Dental College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.willingness to comply with the study protocol. 2.Systemically healthy individuals who are diagnosed with chronic periodontitis. 3.Subjects who are having more than 20 teeth.

Exclusion criteria

Exclusion criteria: 1.Subjects who has undergone antibiotic therapy within 6 months prior the study. 2.Subjects who has allergy to any medications. 3.Pregnant and lactating females. 4.Subjects who were suffering from any systemic diseases and smokers. Unable or not willing to comply with the study protocol. Subjects who take any antibacterial drug within the study period.

Design outcomes

Primary

MeasureTime frame
Reduction of clinical signs of periodontitis, reduction in bleeding on probing, clinical attachment level and periodontal pocket depth.Timepoint: 0 and 90th day

Secondary

MeasureTime frame
Reduction of clinical signs of periodontitis, reduction in bleeding on probing, clinical attachment level and periodontal pocket depth.Timepoint: 0 and 90th day

Countries

India

Contacts

Public ContactHarsha MB

Sri Hasanamba Dental college and hospital

harshamb@yahoo.com9845735007

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026