FindTrial
Sign In

To observe the additional pain sparing effect of the drug (dexamethasone)in addition to primary drug (levobupivacaine or ropivacaine )given as injection in between two muscles in patients who undergo breast cancer surgey.

Comparison of effect of dexamethasone as adjuvant on pain relief after serratus anterior muscle plane block with levobupivacaine or ropivacaine in patients undergoing modified radical mastectomy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/024149
Enrollment
60
Registered
2020-03-23
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Serratus anterior muscle plane block(SAM) with 0.25%levobupivacaine and 8mg dexamethasone.(GroupL): Ipsilateral ultrasound guided Serratus Anterior Muscle block with levobupivacaine 0.2

Sponsors

Department of anesthesia and intensive care government medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: females suffering from carcinoma breast. American Society of Anaesthesiologists (ASA) physical status I ââ?¬â??II. Age ranging from 18-80 years.

Exclusion criteria

Exclusion criteria: Patient refusal. History of relevant drug allergy. History of psychiatric illness and substance abuse. Patient suffering from severe cardiovascular, respiratory, liver, metabolic or neurological disease. Chronic treatment with analgesics. Pregnant patient. Coagulopathy. Infection at planned injection site. Psychological inability of patient to understand.

Design outcomes

Primary

MeasureTime frame
Time to first rescue analgesic and Cumulative morphine consumption over 24 hours in patients receiving SAM block with levobupivacaine or ropivacaine . Timepoint: post operative at 30min , 1hr , 4hrs, 8hrs,12hrs and 24hrs—

Secondary

MeasureTime frame
1.Reduction in pain intensity by VAS score. 2.Total dose of anti-emetics over 24hrs. 3.Any side effects pertaining to the procedureTimepoint: Post-operative at 30mins,1hr,4hrs,8hrs,12hrs and 24hrs. 2.Post-operative at 30mins,1hr,4hrs,8hrs,12hrs and 24hrs 3.Post-operative at 30mins,1hr,4hrs,8hrs,12hrs 24hrs.—

Countries

India

Contacts

Public ContactDr Richa saroa

government medical college and hospital

sanjeev_palta@yahoo.com9646121523

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026